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TNFα therefore aggravates edematous changes and suppresses the fibrotic response of the tissue.
In contrast, reducing the level of the bioactive SL S1P through genetic loss of Sphk1 increases kidney GlcCer and GM3, and therefore aggravates cystogenesis.
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Tile drainage shortens the residence time of water in the soil and may therefore aggravate the diffuse pollution of adjacent surface water bodies.
Recently, we reported that amorphous silica nanoparticles (nSPs), one of the most widely used NMs, enhance antigen-specific cellular immune responses and may therefore aggravate immune diseases.
The Gregorian reform movement therefore aggravated the age-old contradictions in Germany's early medieval constitution, but its monastic culture and its intellectual interests were anything but barren.
Therefore, aggravating effect of examined polymorphism in MOH patients could be driven by its proneness to develop an impulsivity dyscontrol, the cornerstone of any substance abuse disorder.
TAT could therefore aggravate the initial damage done by singlet oxygen.
However, RAAS inhibitors also reduce haemoglobin levels and may, therefore, aggravate anaemia.
Thus, enhanced inflammation and therefore aggravated tissue damage are expected to promote more efficient transition of Stx into the blood stream and thereby increase the probability to develop HUS.
Genes encoding for growth factors or enzymes that account for alveolarization through proper secondary septation and extracellular remodeling might affect the gas-exchange and therefore aggravate respiratory distress at birth.
Cerebral hypoperfusion and raised ICP may result in an imbalance of energy supply and demand especially for the injured brain and, therefore, aggravate the risk for metabolic distress and brain tissue hypoxia [ 10- 16].
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CEO of Professional Science Editing for Scientists @ prosciediting.com