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Therefore, activating GS may provide a potential approach for the treatment of type 2 diabetes.
Moreover, the increased pyruvate goes down through pyruvate dehydrogenase (PDH) to acetyl-coenzyme A (AcCoA), where AcCoA becomes homeostatic, namely, the increase in AcCoA activates Ppc reaction [123,124], thus reducing the upcoming Pyk-PDH fluxes, increases oxaloacetate (OAA), and activates citrate synthase (CS) reaction, and therefore activating the outgoing flux from AcCoA.
It produces patterns that are called Wave Frequencies that can predict how resilient someone can be at managing stress and sleeping peacefully; therefore activating the right frequency is the key to tone down noise and the ripples of our mind.
Therefore, activating effects induced by agonists must break these constraints to enable the shift towards the active state.
Stable microtubule-kinetochore interactions are established only 8 hours after GVBD [15], therefore activating the APC/C too early may have severe consequences because oocytes may still not have had enough time to establish stable microtubule-kinetochore interactions.
Therefore, activating mutations of K-ras were not a common occurrence and was not an explanation for MYC independence in our lung model, in contrast to what has been previously reported for breast cancer [16], [17], [20].
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Aha1 was seen to modulate the so-called catalytic loop of the middle domain of Hsp90 and therefore activate its ATPase activity.
This protein, which possesses a HAT activity, can therefore activate basal or induced expression of ABCB1 gene (Hu et al, 2000; Friedman et al, 2002; Tanaka et al, 2003).
Running therefore activates both coagulation and platelet activity, resulting in an increased risk of thromboembolic incidents in running athletes.
GraB can therefore activate two independent pathways to caspase activation that bypass anti-apoptotic proteins commonly elevated in cancer.
Therefore, activated GR monomers control gene expression by modulating the transcriptional activities of those transcription factors, without direct binding to DNA.
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