Sentence examples for therefore a rationale from inspiring English sources

Therefore, a rationale exists to use BH3 mimetics to circumvent apoptosis resistance in these cancers.

There is therefore a rationale for a synergic effect of these two SNPs in HCC carcinogenesis.

There is therefore a rationale in studying the effect of endothelin antagonists in breast cancer patients with bone metastases.

There is, therefore, a rationale and urgent need to develop strategies to treat delirium in critically ill patients.

At the same time, there is convincing evidence of a dose response relationship, and therefore a rationale for increasing doses when possible.

The joint self-governing body of the German Health Care System gave therefore a rationale in late 2003 for the introduction beginning in 2004 of minimum volume standards on five surgical interventions.

Our results therefore provide a rationale for the abundance of aromatic amino acids in fibril-forming peptides and establish important roles of cross-strand Tyr ladders in the structure and stability of β-rich peptide self-assemblies.

This study therefore provides a rationale for clinical biomarker studies in humans.

These findings therefore support a rationale for targeting the death receptor pathway, as a strategy for bypassing platinum resistance.

This study therefore provides a rationale for hypothesis-based biomarker-driven clinical trials using PARP inhibitors or other DNA damaging agents in patients with prostate cancer.

Collectively, these studies suggest that targeting Skp2 may be an ideal therapeutic strategy for human cancer, therefore establishing a rationale for designing small molecule inhibitors of Skp2 for the treatment of human cancers.