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In this study we present an approach where the DrugScore potentials are not only used to evaluate ligand poses, but rather to optimize and thereby relax a ligand conformation under the influence of these potentials.
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Insurance makes defaults less likely, thereby relaxing the country's borrowing constraint, and enhancing its access to capital markets.
Beta blockers such as propanolol and atenolol decrease blood pressure by blocking the nervous systems response to stress and thereby relaxing the heart muscle.
The resulting error detection and correction procedures can then be performed periodically, thereby relaxing the reliability requirements and overhead associated with the checking mechanism.
The integro-differential formulations reduce the order of spatial derivatives, thereby relaxing the stability constraint and allowing large time steps in an explicit numerical scheme.
No restriction is placed on the degree of curvature of the shell, thereby relaxing the strictures associated with shallow shell theory.
A possible physical mechanism of the LVMs is that P dopants break the translational symmetry of ZnO, thereby relaxing the conservation of wave vector; and they can lead to scattering by phonons in ZnO materials that have wave vectors far from the zone center.
Our study indicated that UV irradiation stimulated the HAT activity of p300 and led to increased histone acetylation, thereby relaxing chromatin structure and promoting MMP-1 activation.
The rationale behind this approach was that with growing domain families, more distantly related members become associated with a conserved domain profile, thereby relaxing the profile and making it more sensitive.
Moreover, fishing reduces population size, thereby relaxing intra-population competition of the harvested population.
The latter removes the positive charge on histones, thereby relaxing the condensed chromatin structure to promote gene transcription [ 48, 49].
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CEO of Professional Science Editing for Scientists @ prosciediting.com