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Indeed, IDC have been shown ex vivo to bind directly to the RS domain of SR proteins and thereby impede its phosphorylation.
Our results indicate that HS at the surface of cancer cells sequesters CAPs away from the phospholipid bilayer and thereby impede their ability to induce cytolysis.
Importantly, increased generic competition in poor countries is unlikely to significantly impact the revenues of patent-based pharmaceutical companies and thereby impede future innovation.
We therefore propose that the long, unbranched HS chains can sequester the lytic peptides away from the phospholipid bilayer and thereby impede their ability to induce cytolysis of the target cells, as shown in Figure 8.
Therefore, it is feasible that up-regulation of HR factors due to the inhibition of miR-1255b, miR-193b*, and miR-148b* in G1 cells may also de-stabilize the balance of the HR and NHEJ pathways and thereby impede DSB repair.
This idea is supported by the findings that estrogen increases the number and activity of endosteal osteoblasts [ 22], which are critical mediators of stem cell dormancy and survival [ 23]; estrogen may thereby impede the ability of ZA to decrease disseminated tumor cells.
Similar(54)
The unacknowledged purpose — explained to Gore only afterward, Shrum insists — was to snarl traffic, thereby impeding Bradley supporters driving to the polls.
This would increase already-high unemployment, expose excessive financial risk-taking, embolden Russia, and strengthen populist movements further, thereby impeding comprehensive policy responses.
These ideas were generally held until the 16th and early 17th centuries, thereby impeding an understanding of the true principles of motion and precluding the development of ideas about universal gravitation.
In 1953, a critic from the London Times said of a local recital, "Joyce Hatto grappled doggedly with too hasty tempi in Mozart's D Minor piano concerto and was thereby impeded from conveying significant feelings towards the work, especially in quick figuration".
The hole in the diaphragm allows the abdominal viscera to invade the thoracic cavity, thereby impeding normal lung development.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com