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They can bind to the active site of a protein or enzyme, thereby blocking its activity.
Denosumab inhibits RANKL, thereby blocking osteoclast activity2,12,26,44.
A secreted protein that binds to IL-1R, thereby blocking IL-1R downstream signalling.
The idea is that the cow's immune system would make antibodies to attack the proteins, thereby blocking the attachment.
The herbicidal inhibitor norflurazon binds at a plastoquinone site thereby blocking reoxidation of FADred.
Bisphosphonates are a heterogeneous group of bone-targeting agents, which are absorbed by active osteoclasts, thereby blocking their activity85.
If they are veering left and I try passing to the right, they suddenly change direction and start heading right, thereby blocking the entire sidewalk.
Biomimetic detectors, Ms. Peets said, use chemicals that darken when carbon monoxide is present, thereby blocking an internal light source from reaching a receiver and sounding the alarm.
These small molecules inhibited the low pH-induced conformational change of hemagglutinin, thereby blocking viral entry into host cells.
These peptide toxins bind to the outer vestibule of the channel pore thereby blocking ion conduction through NaV channels.
It must be something that changes shape over time, thereby blocking different levels of light at random intervals.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com