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STE5 and ARO1 each bear a second silent mutation that may be present due to close genetic linkage to the productive mutation or lead to a non-obvious phenotypic modification, such as altered mRNA stability, and thereby arise in R57 through selection.
The higher the IAP increases, the more extravasation of fluids on one hand (thereby with arising intravascular dehydration) and a thickening of interstitial tissues on the other hand (thereby with arising elongation of diffusion courses) seem to additionally aggravate pressure-induced tissue ischemia and histomorphological damages.
Thereby question naturally arises as to whether these theoretical researches can directly be applied to practical situations in various seas/oceans around the world.
One of the advantages of reducing regulatory restrictions on land use is that it allows developers, property owners, and others to respond to demand as it arises, thereby keeping costs down, and quantity up.
In this way, these models capture a broad range of possible dynamical behavior; while such predictions are necessarily imprecise, dynamic Boolean models are attractive in that they do not require extensive parameterization (and thereby capture behavior that arises from the fundamental characteristics of the interactions between system components).
This explicit method tracks concentration profiles in the upwind direction and thereby avoids instability arising from flow reversal.
To overcome the first limitation, inducible forms of the Cre recombinase were developed to allow for temporally controlled somatic mutagenesis thereby circumventing problems arising from constitutive Cre recombinase activity [2].
A dense SNP panel will be informative about the haplotype on which the repeat polymorphism arose, thereby providing a proxy for the repeat.
As a test tool reciprocal illumination may be used, i.e., the resulting tree can be tested whether the evolutionary scenario arising thereby is plausible or not.
