Sentence examples for thereby activate from inspiring English sources

While several enzymes are capable of producing PA, the particular species of PA produced by PLD1 are preferentially bound by FRB domain and thereby activate mTOR kinase activity by displacing DEPTOR, an endogenous inhibitor of mTOR [ 41].

In this case, we found that phosphorylation of S184/T282 in the center domain of ZBTB16 by GSK3β may provide a signal to disrupt the inhibitory folding and thereby activate its auto-ubiquitination activity.

Constitutive activation of FGFR3 will probably cause constitutive activation of p38 MAPK and thereby activate the entire p38 MAPK signalling pathway.

A notable example is isochorismate synthase [18], in which a catalytic lysine is proposed to deprotonate and thereby activate a nucleophilic water molecule.

Bacteria release metabolites and toxins and thereby activate the immune system.

Dendritic cells present the antigens to naïve T-cells and thereby activate them.

Hyperactivation of PARP-1 depleted ATP pools in dopaminergic (DA) neurons, thereby activating AMP-activated protein kinase (AMPK).

This inactivates sororin and thereby activates the releasing activity that triggers cohesin's dissociation from chromosomes.

Trib3 inhibits Akt activity and thereby activates FOXO3a, which in turn binds to and activates the trib3 promoter.

Oxidative stressors can cause Nrf2 to translocate to the nucleus, thereby activating the Nrf2 pathway [21].

By changing the tongue position and thereby activating different sensors, the user sets control commands.