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DOX-CNPs showed biphasic release kinetics: initially a faster release profile wherein about 25% of the drug is released in 12 h and thereafter sustained release for days (∼50% of DOX was released in 7 days).
This study documents that a rapid decline in A1C can be achieved during pregnancy when normoglycemia is vigorously instituted and achieved and thereafter sustained for 4 weeks.
Thereafter, sustained by children and later grandchildren, she also found some solace in working for the Royal Academy of Dancing on technical advice, while living in London, but as a performer had given up ballet for good.
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"For [philosophy] does not admit of exposition like other branches of knowledge; but after much converse about the matter itself and a life lived together, suddenly a light, as it were, is kindled in one soul by a flame that leaps to it from another, and thereafter sustains itself".
Even though the virus may not trigger autoimmune disease, it may be reactivated by an initial inflammatory insult and thereafter sustain and exacerbate inflammatory processes by producing type I cytokines and by specific mechanisms that induce inflammation and autoimmune reactions.
In contrast, dapagliflozin response was initially smaller during titration but thereafter was sustained during the maintenance period such that it was identical to glipizide response at 52 weeks.
The first is the necessity for a loading dose at the beginning (the first day or two) of a treatment regimen and the considerably lower dose requirement thereafter to sustain suppression.
While the original defect of memory may have been largely, if not wholly, organic, it was sustained thereafter on a hysterical basis.
Winners of Breeders' Cup races seem to fall into a range of categories, among them horses that already are bona fide stars that reaffirm their supremacy; horses that are one-shot wonders whose victorious Breeders' Cup form isn't sustained thereafter, and horses that step into the spotlight to be crowned the sport's newest champions.
We see peak release of drug within 1 hour and this is sustained thereafter.
Injuries sustained thereafter and prevented him from appearing in the remaining Tests of the series.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com