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The results from the PIER trial in which ranibizumab was given monthly for 3 months and quarterly thereafter indicate that VA improvements with mandated quarterly administration were not as robust as with a monthly schedule (Kaiser et al. 2006c; Anon. 2007a).
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MeOH conversion linearly increased with increasing electroless deposition time from 0.5 to 10 min and appeared to plateau thereafter, indicating that 10 min was the optimal loading time.
The PCE, however, increased initially before reaching a maximum and decreasing thereafter, indicating that an enlarged surface area arising from a higher-aspect-ratio profile may degrade the PCE performance after long etching times.
Diagnosis assays carried out as described thereafter, indicated that about 90% of all dengue-infected children had secondary infection.
The phenotype of individual Avy mice seems to be determined early in embryogenesis and maintained thereafter, indicating that in somatic cells the epigenetic state is stable.
Oocytes from all groups shrank quickly during approximately the first 2 min of sucrose exposure, and the shrinkage decreased thereafter, indicating that they were slowly reaching the equilibration state.
RTVs in mice undergoing cryotherapy alone or simultaneous combination appeared stable for 3 days post-treatment, but increased steadily thereafter, indicating that the actions of these therapies were only partial.
Proteinuria, a surrogate for glomerular vascular permeability, inflammation, and kidney damage, was detected in MRL/ lpr mice, but not in MRL/Mp mice, by 16 weeks of age and increased thereafter, indicating that progressive kidney damage was occurring.
However, the PFS curves crossed at ~6 months after the start of treatment, favoring the chemotherapy group during the initial 6 months and gefitinib thereafter, indicating that the beneficial effect of gefitinib on PFS might be limited to those patients who harbored activating EGFR mutations.
Water contact angle decreased significantly (* p < 0.05) after a brief 30 s treatment, from 80.9 ± 4.6° to 52.3 ± 10.6°, and was unchanged thereafter – indicating that a treatment time of 30 s may be sufficient to permit cellular attachment and growth (Fig. 4).
In liver from control mice, MPO activity increased sharply to a maximum already reached 6 hours after LPS injection, then dropped by 65% in the next 6 hours and decreased more progressively thereafter, indicating that liver recruited leucocytes for transient infiltration.
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