Sentence examples for there were substantial problems from inspiring English sources

However, in the two latter studies there were substantial problems with the implementation of the intervention or loss to follow-up, respectively, and this may have reduced the apparent effectiveness of the interventions [ 17, 18].

Based on our assessments of the documents we could obtain, we came to the conclusion that there were substantial problems with the design, conduct and availability of information from many of the trials".

"While Infosys is not admitting any wrongdoing, its leadership did appreciate there were substantial problems in the way they were conducting business in this country," said John Malcolm Bales, the United States attorney for the Eastern District of Texas, in Plano.

There are substantial problems to solve".

"Despite the prosperity within the city, there are substantial problems of deprivation in parts of Bristol," the report said.

There are substantial problems to assay the sn-1 acylation activity of lysophospholipid acyltransferases because the sn-2 lysophospholipid substrates are unstable due to rapid acyl migration to the sn-1 position.

However, on launch, there have been substantial problems with multiplayer access, itself the reason for delaying this review.

There were substantial overlaps between problems identified by the different language screening methods.

> -wrap-foot> There were substantial normative misperceptions in this general population sample of problem drinkers.

There were substantial movements during the campaign.

There were substantial shifts from the late 1960s onwards.