During autophagy there is sequestration of cellular material into double-membrane vesicles called autophagosomes.
A possible explanation for this finding may be that, initially, there is sequestration of 2-MeOE2 bintoTE into blood components, possibly RBCs (unpublished data), or binding to plasma proteins, resulting in high AUC orally.
O'DONNELL: Congressman, it's my understanding that as part of the Budget Control Act there was not just the sequestration, the defense sequestration, but there is also $1 trillion in immediate spending cuts, which included the defense cuts, almost $400 billion that were proposed by the chairman of the joint chiefs of staff, Mr. Dempsey, as well as Secretary Panetta.
There was no sequestration of aggresomes with αAwt co-expression with the truncated constructs, αA162 and αA168.
Moreover, there was no sequestration of aggresomes in αA-wt co-expression with these truncated constructs suggest that it co-aggregates with the unfolded protein products of the αA162 and αA168 and localized into the perinuclear sites of the cells.
There was no sequestration and no intravascular or perivascular pathological features in the CM3 and COC groups.
Similarly, there was no sequestration in the brain, where oedema and haemorrhages have been described in P. chabaudi infected il10−/− mice (Sanni et al., 2004).
If the fracture resulted in non-union so that the extremity was no longer used, there was gradual sequestration of the dead bone in the course of one to two years.
And there would still be sequestration — blind cutting — under Plan B. There was another B under discussion, though: betrayal.
