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"there are significant differences in" is a correct and usable phrase in written English.
You can use this phrase when referring to the differences between two or more things, typically in the context of comparing and contrasting. For example: "There are significant differences in the lifestyles of people who live in urban areas and those who live in rural areas."
Exact(60)
In addition there are significant differences in feed composition in some of the studies.
Although this core fold is conserved, there are significant differences in Cas6 enzymes from different species.
There are significant differences in survival between cases with different tumor grades.
What is more, there are significant differences in the cardiac function between different mouse strains [ 13].
There are significant differences in development time for standards involving different organisation types and countries.
The study should be halted if there are significant differences in the level of overall significance, α.
There are significant differences in socioeconomic and health status among different regions in China.
However, there are significant differences in the amount of protein binding to the different surface types.
Conclusions: There are significant differences in frequency of limb occlusion and endoleak between groups with different endovascular devices.
Certainly, there are significant differences in outlook.
But there are significant differences in the present case.
More suggestions(17)
there are appreciable differences in
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there are notable differences in
there are significance differences in
there were important differences in
there are important differences in
there are vast differences in
there are large differences in
there are substantial differences in
there are considerable differences in
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com