Sentence examples for therapeutics using the from inspiring English sources

Exosome release, a multipotent therapeutic 12. Proteasome release for clearing misfolded proteins Development of therapeutics using the SRM of adult stem cell types leads us to a very different kind of therapeutic development than those offered by the development of small molecules or biologics.

In this 'State of the Union'-type review, we highlight recent advances in the design of bone regenerative therapeutics using the primary elements of stem cells, growth factors and scaffolds, and identify major obstacles in their paths to the clinic.

This review seeks to illustrate the numerous challenges that are encountered during the development of nanoparticle-based therapeutics using the commercially available protein-bound nanoparticle formulation of paclitaxel (Abraxane®, Celgene Corporation) as an example where relevant.

Here, we prove that a P-gp/BCRP-driven pharmacoresistance limits the bioavailability of ALS therapeutics using riluzole, the only FDA-approved drug for ALS and a substrate of P-gp and BCRP.

RNA interference (RNAi -based theRNAi -basedsing siRNA have therapeuticsl to silence disease-causing genesiRNA

Of course, the most significant clinical application would be to develop metastasis-inhibiting therapeutics using targets deduced from the biological knowledge provided by the MAF signature.

That study will have set the stage for an entire class of therapeutics, using bacteria as drug delivery systems and using the kinetics of bacterial growth as a mechanism for titrating therapy.

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The surprisingly high incidence observed in common marmosets, which might be due to a limited variability in their major histocompatibility complex loci [ 11], allows the evaluation of the efficacy of therapeutics using a small number of animals.

Similar results were demonstrated in mice grafted with colorectal carcinoma transplants, administered with anti-MIF therapeutics, using either MIF-antibodies or the MIF antagonist (S, R -3- 4-hydroxyphenyl -4,5-dihydro-5-isoxazole acetic acid methyl esteR -3- 4-hydroxyphenyl -4,5-dihydro-5-isoxazole

Furthermore, we were able to predict novel therapeutics using our emphysema gene signature and the Connectivity Map, showing that the compound tripeptide Gly-His-Lys (GHK) reversed the emphysema-associated gene expression changes [ 16].