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All studies were retrospective comparative cohorts, level III therapeutic studies [13, 14, 16, 17] (Table 1).
No statistically significant body weight loss was observed in either of the therapeutic studies.
Therapeutic studies using transgenic rodent models often fail to predict efficacy and outcome in human patients.
Therapeutic studies indicated that vaccination with pConE6E7 prevented or delayed the growth of tumors.
The present investigation consisted of three different studies: one biodistribution and dosimetry study including MRI examinations and two therapeutic studies.
d Mean animal body weight in therapeutic studies 1 and 2 (note the scale of the y axis).
In view of its potentially important role in migraine, surprisingly few therapeutic studies have been performed with NOS-inhibitors.
GOT1-bearing BALB/c nude mice were divided into three studies: one biodistribution and dosimetry study and two therapeutic studies.
All therapeutic studies in NMO have been either small, retrospective case series or uncontrolled prospective studies.
The DSQ should therefore be considered as a viable PRO measure for use in future therapeutic studies of EoE.
Therapeutic studies constituted the majority of study type (85.7 %) with economic study types in the minority (1.3 %).
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