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Although Dr. Zamecnik's antisense concept was first met with skepticism, it has given rise to a new class of therapeutic compounds called antisense drugs, which are under active development in the biotechnology industry.
The new apparatus and methods described herein could be used across a wide range of biomaterials and therapeutic compounds.
A summary of the therapeutic compounds discussed in this review is listed in Table 1.
Amyris recently launched its µPharm™(microPharm) discovery and production platform to provide the pharmaceutical industry with therapeutic compounds that are scarce, unavailable, or cost-prohibitive to produce via chemical methods.
Thus, both intuition and rational analysis of databases can be used to generate effective therapeutic compounds.
From systematically generated informatics data analysis, one would be able to evaluate the physiochemical properties of the potential therapeutic compounds.
A major concern of medicine today is the sustained release of therapeutic compounds.
Our research provides a valuable tool for designing new therapeutic compounds with desired biological activity.
Proteins and peptides are excellent therapeutic compounds which have highly specific and potent biological functions.
We took an agnostic empirical approach to find PO therapeutic compounds.
For example, only 1 in 10,000 potential therapeutic compounds makes it through the drug development pipeline to the marketplace.
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