Each theoretical variant has an expression for the compressibility factor Z=P/(ρ R T), essentially providing the equation of state for the liquid.
In addition, there are large numbers of theoretical localization variants, allowing false localization rates to be determined.
Despite all our efforts, we could not detect by RT-PCR, the mRNAs of Δp53 or of its theoretical spliced variant Δp53 β, Δp53 γ, Δ133Δp53, Δ133Δp53 β and Δ133Δp53 γ in 21 normal human tissue analysed nor in numerous tumours of several human tissue origins.
To get an idea of how much the various mutations would affect the overall structure of the Spy-client complex we show below a complex model based on the modeled structure of a theoretical Spy variant that contains all four of the key activity-enhancing mutations (Q49L, H96L, Q100L, F115L) and modeled its binding with the Im7 7-45 peptide.
Based on the theoretical examination, rare variants can show a stronger pattern of population stratification than common variants, particularly in the presence of sharp spatial distributions for non-genetic risk of disease (62).
Shuffling of three genes divided in 9 modules (9 sets of modules, each set containing 3 modules) provides a theoretical number of variants of 19,683 and shuffling of four or five genes would provide a maximal theoretical diversity of 262,144 and 2 million combinations, respectively.
In support of the theoretical result, such variants were frequently observed in high linkage disequilibrium in their results.
The theoretical risk of variant Creutzfeldt-Jakob disease and the consequent introduction of leucodepletion by UK blood services has significantly increased the cost of blood to the National Health Service.
By distinguishing deformation variant from orientation variant, the theoretical connection and distinction between PTMC and phase field microelasticity theory are discussed, and their predictions are compared with experimental observations.
While they have been very influential historically, especially their Christian variants, as theoretical propositions I believe they rest on core premises which are too contentious and exclusionary.
