In 2004, he started taking small, and then increasing doses of the drug.
Since then increasing numbers have been trying to escape by sea to Malaysia, Indonesia and Thailand.
But he persevered, running 30 miles a week for the first couple of weeks and then increasing his mileage.
I spent hours on their floors, sorting, while they watched, with bewilderment and then increasing amusement as they got older".
That might mean accepting shorter lease lengths, with a view to refurbishing a building on expiry and then increasing rents.
The ocean gliders travel by slowly decreasing their buoyancy to sink, and then increasing it again to rise.
First it was gentle but insistent prodding then increasing derision rising to a damning indictment, and Chloe Smith's ministerial career was all but over.
The company ended up suspending production for one night and then increasing output during morning and afternoon shifts to meet demand.
But if that's the picture that school holidays conjure up in older minds, then increasing numbers of stressed-out teenagers would like to put the record straight.
If low serotonin levels were really what made you feel depressed, then increasing levels of serotonin should alleviate the symptoms right away.
Khalaf said what Turing had done sounded more like trading – buying up the rights to a drug and then increasing the price.
