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Therefore, in tumours where the p53 signaling pathway is lost/mutated the TRAIL agonists in combination with ER stressors may be of better therapeutic benefit than their utilization in combination with genotoxic drugs.
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Their usage in combination with conventional chemotherapeutics holds a number of potential advantages over combinations with synthetic compounds.
Still, possible increases in resource utilization, in combination with the elevated prices of energy and other commodities, have the potential to add to inflation pressures.
The metric needs to take into account each machine tool components' efficiency and the need-oriented utilization in combination with the other components while referring to efficiency limits.
To our knowledge, few studies have used electronic MHS records as an outcome of MHS utilization in combination with predisposing variables from both electronic medical records (EMRs) and self-reported questionnaires.
An advantage of focusing on linked utilization, in combination with the alignment efforts, is that it directs the attention to what researchers and others can do to enhance the realization of beneficial contributions.
The aim of this study, therefore, is to compare the utilization of protein supplements, assess their frequency of use and their consumption in combination with other dietary supplements.
Furthermore, the utilization of HBr in combination with KI in the deprotection step resulted in higher RCYs compared to HI alone.
More recent research showed that the utilization of QDs in combination with GFP labeling can differentiate tumor vessels from both perivascular cells and the matrix, and QDs linked to bone marrow-derived precursor cells can visualize tumor vasculature [ 142].
Since androgen deprivation induces TGF-β signaling in prostate cells [ 32- 34], it is tempting to speculate that ERG-induced suppression of androgen signal transduction leads to an increase of TGF-β pathway utilization which - in combination with WNT signalling - results in EMT and cell invasion in fusion-positive tumors.
Use grenades in combination with other weapons.
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