Exact(8)
Some compounds, such as 1a, 1e, 1g and 1h are promising because of their high activity against leukemia and their low activity against normal hematopoietic cells.
Although there were multiple β-glucosidase proteins present in the culture filtrate, only a single prominent β-glucosidase protein with maximum enzyme activity was clearly visible, while other proteins were not digitally captured due to their low activity (Fig. 3b).
Even high concentrations of phenol, resorcinol, and catechol did not interfere with 1-naphthol determination, probably due to their low activity in azo coupling with SiO2 DS, as discussed above.
The only limitation of the corresponding catalysts is their low activity related to the low concentration of zeolite outer sites, which should be easily overcome by preparing zeolite samples with larger outer surface.
Finally, because of their low activity levels, task allocation mechanisms should consider suggesting a same question to multiple experts or to a combination of experts and highly active users to increase the chances of obtaining an answer in a reasonable time.
In total, 73% of the clusters exhibited oscillations (71% of the CNT clusters and 74% of the PDL clusters), 20% did not show detectable oscillations and 7% were not analyzed due to their low activity.
Similar(52)
We show that the low activities of PKB/Akt and Jnk are responsible for the increased cell death of late HF1 cells, and that their low activities during stress enable p53 induction and initiation of apoptosis, when deprived of IGF1, and nutrients.
The VpCDPK genes with decreased transcript abundance might not participate in the signaling response to cold stress but their low activities might result in pervasive down-regulation of transcription.
As a result plasma membrane H+-ATPases are locked in their low-activity state, leading to an alkalinisation of cell walls instead of acidification and interfering with expansin-driven weakening of the walls [ 12].
However, alkyl (3b d) or phenylamino carbonyl methyl compounds (7h i) did not give favorable activities because of their either low activity or high cytotoxicity.
Despite their very low activity at pH 7 on the model substrates, both laccases were able to reduce the concentration of these micropollutants significantly at neutral pH, which is for the first time reported for bacterial laccases.
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