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File structure system has several configurations, each of which have their functionally equivalent yet an independent configuration written in different programming logic.
Slevin et al. in this issue of Structure reveal the architecture of a hidden set of polo boxes from the divergent PLK4, a critical player in centrosome duplication, shedding new light on the evolution of PLKs and their functionally related kinase ZYG-1.
First, their functionally important properties may develop continuously.
Chaperones are proteins that assist RNA and protein molecules to reach their functionally folded states.
In particular, some inhibitors with lower K i values oligomerize at NMR spectroscopy observable concentrations but remain as monomers around their functionally effective concentrations.
The study provides an interesting view of the interface between aspects of a transcriptional regulator that are highly conserved and their functionally divergent applications in evolutionarily distant species.
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The union of the set of known biomarkers and their functionally-related genes represented the "network seeds".
On the other hand, for some of differentially regulated metabolites identified, such as urea and cyanophycin, no change was observed for their functionally-related genes in the transcriptomic datasets, which may be due to multiple factors, such as the snapshot nature of the analysis and the different stability of RNA molecules [ 25].
Only a few genes involved in the DNA repair process have been characterised and their functions have been functionally validated in monocot crops, including rice [ 14].
It takes an hour or two to process each package, "an obstacle that makes their job functionally impossible," according to a 2003 Congressional investigation.
Therefore, we tested the expression levels of these two genes in their most functionally relevant tissues: SALL1 in kidneys and PTEN in the bone marrow.
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