Sentence examples for their folding pathways from inspiring English sources

More information has also become available about their folding pathways.

This apparently indicates the presence of parallel folding pathways even if folding occurs over a single homogeneous transition state.

The modulation of the folding energy landscape of monellin by GroEL occurs because GroEL binds folding intermediates on parallel folding pathways, in different ways, and with different affinities.

Molecular chaperones are believed to prevent undesirable folding pathways such as premature folding, aggregation and misfolding and thereby facilitate formation of biologically active protein structures [ 9].

We present evidence that the folding pathways and kinetics of hierarchically folding clustered sequence are not adequately described in conventional MC simulations, and the account for cluster dynamics provided by CMC allows to capture essential features of the folding process.

In addition to observing previously established folding pathways, a pathway with an observed folding rate constant of 1 per second was discovered.

Proteins with heterogeneity in the folding pathways may have been evolutionarily selected so that folding is ensured under very different conditions possible in the cell [35].

Two general principles are used extensively to describe the folding pathways on the energy landscape [5], [25]: During folding, proteins (i) try to evade high energy regions of the folding landscape, and (ii) prefer low entropy loss routes.

Furthermore, the ensemble of folding pathways proposed here substantiates a rational drug design strategy based on inhibiting the folding of HIV 1 protease.

In the overall folding process, intermediate folding states and multiple folding pathways were observed.

The folding energy landscapes appear highly plastic, with small perturbations re-routing folding pathways.