PZ-39 has no effect on ABCB1 and ABCC1-mediated drug efflux, resistance, and their expression, indicating that it may be specific to ABCG2.
Usually their expression does not change in the experiment but their expression indicates their participation in signal transduction.
A substantial number of asRNAs significantly change their expression, indicating that their putative regulatory effects may be important during the conditions tested.
20E treatment induced the expression of these ABCG genes in the midgut and RNA interference-mediated knockdown of USP, a component of the 20E receptor, decreased their expression, indicating that these midgut-specific ABCG genes are 20E-responsive.
Although no peptidoglycan has been found in land plants, the ubiquity of AEE genes in land plants and the evidence of their expression indicate that they are functional and may play important roles in the growth and development of plants.
Von Gloeden paid them for their time before his lens, and their expressions indicate that they trusted him and enjoyed the game.
He bets on his daughter's name, and his associates stand there in some gambling den in Atlantic City, watching the screen and dutifully rooting for Meadow's Gold, but their expressions indicate they know the horse is going to lose.
It has been observed that the expressions of fractalkine and its receptor CX3CR1 are upregulated in atherosclerosis lesions, and the severity of atherosclerosis is greatly improved by inhibiting their expressions, indicating that the fractalkine/CX3CR1 pair is closely related to atherosclerosis.
In summary, miRNAs exhibited a more complex regulation on their target expression, indicated by both repression and activation at levels of transcription and translation.
Additionally, heat map diagrams were created to display the number of differentially expressed genes that were annotated to the GO Biological Process terms listed in Figure 3 and to visualize the magnitude and direction of their differential expression (indicated by the SLR).
