Sentence examples for their essentiality from inspiring English sources

Twelve drug targets showed up to be non-essential in both networks (Table 1), although their essentiality is experimentally validated for the parasite.

By Paul Brodeur The New Yorker, January 15 , 1966P. 23 Comment on the subway & bus strike; about people who do drive into the city to prove their essentiality, and about coming upon two men sanding & painting the horses on the merry-go-round in Central Park.

Comment on the subway & bus strike; about people who do drive into the city to prove their essentiality, and about coming upon two men sanding & painting the horses on the merry-go-round in Central Park.

This review deals with recent studies on drug targets and exploring their essentiality for the survival of Leishmania.

Interest in metals like zinc (Zn) and copper (Cu), which are required for metabolic activity in organisms, lies in the narrow "window" between their essentiality and toxicity.

The advantage of using such hub proteins as drug targets lies in their essentiality, non-replaceable position in the PIN and lower rate of mutation, which can help to counter bacterial resistance.

That the targets inhA and embB differed so dramatically in their survival kinetics is probably explained by their contrasting essentiality in M. smegmatis.

Any oxidative phosphorylation reactions or diffusion transport reactions that had not previously been added to the model are appended given their obvious essentiality.

Of the 129 targets that do not pass the filters used in our study, but were predicted by Anishetty et al, 77 have been eliminated due to their non-essentiality in Mtb, as predicted by systems-level analyses, clearly demonstrating the need for incorporating systems-level studies.

After duplication, genes appear to continue to undergo purifying selection with their evolutionary rates and genomic persistence depending on their level of essentiality [ 21].

Highly connected proteins, or "hubs", have classically characterised vulnerable points in a network due to their role in a large number of interactions and due to their association with essentiality [ 9- 11].