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The nodes are then ranked in descending order of their centrality values.
To decipher the development of node centrality between birth and adulthood, we present in Figure 4 the newborns immune trees shown in Figures 3B and 3D, while coloring the nodes according to their centrality values as calculated for the maternal networks (Figures 3A and 3C).
Thresholds for selection criteria of the most relevant nodes according to their centrality values were established considering one s.d. of the mean for each topological network properties: 'stress': 48 919.44 (mean=15251.9); 'connectivity or degree': 35.84815 (mean=19.59893); 'betweenness': 0.022270086 (meand0.005765439); and 'closeness': 0.372488254 (mean=0.372488254).
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The colour of the nodes represents their eigenvector centrality inside the community with a light blue/blue/violet/red scale for increasing centrality values; the radius represents their degree in the full graph.
Generally speaking, large centrality values are assigned to central nodes in the network.
Their values play a decisive role in obtaining Katz centrality values that fluctuate.
As a case in point, functionally important sites in GroES present the largest centrality values in GroES coevolutionary network, indicating their greater evolutionary dependencies with other sites closely located in the protein structure.
Their values play a decisive role in getting fluctuating Katz centrality values.
Benzi et al. [27] in their paper, showed that different choices of (alpha) and (beta) lead to different centrality values.
The Spearman rank correlation coefficients between the p-values of GO terms calculated for the most central nodes according to particular indices in particular networks and the node centrality values of the nodes.
Furthermore, we exploit hardware and software vectorization to compute closeness centrality values on CPUs, GPUs and Intel Xeon Phi.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com