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An important element of these evidence-based therapies is the gradual, systematic exposure to traumatic memories until their capacity to trigger distress diminishes.
Although counteracting innate defenses allows oncolytic viruses (OVs) to better replicate and spread within tumors, CD8+ T-cells restrict their capacity to trigger systemic anti-tumor immune responses.
One of the key issues with bispecific antibody is their capacity to trigger an efficient cell-mediated cytotoxicity.
We investigated the inflammatory response to conidia and hyphae of A. fumigatus and specifically, their capacity to trigger activation of an inflammasome.
Although LXs are AA-derived eicosanoids, they can be clearly distinguished from the classical proinflammatory prostaglandins, thromboxane, and leukotrienes on the basis of their capacity to trigger a self-limiting response to inflammation when generated by leukocytes.
These ligands have been shown to bind the 1G4 TCR with lifetimes spanning a sevenfold range as measured under 2D 15 and 3D 13 conditions, which correlated with their capacity to trigger interferon-γ production 13.
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Their different capacity to trigger complement activation established on the cleavage of the protein C3 was also already described making these nanoparticles good models to investigate the relation between the molecular feature of their corona and the mechanism by which they triggered complement activation.
It is probable that PM rich in prooxidative chemicals, such as combustion-derived particles [from, e.g., urban settings (Brook et al. 2009)] and/or smaller ultrafine PM [e.g., diesel exhaust particles (Lucking et al. 2011)] are more apt to promote systemic endothelial dysfunction because of their potentially greater capacity to trigger oxidative stress and inflammation in vivo (Brook et al. 2010).
Motor systems manifest a great deal of flexibility, including their ability to adjust to changes in muscle size with growth and exercise, thus maintaining the capacity to trigger effective muscle contractions.
The current findings indicate that differences in nociceptive processing in the superficial and deep dorsal horns extend to the descending control of their A- and C-nociceptor input, and that non-selective control of the superficial dorsal horn has the capacity to trigger differential control in the deep dorsal horn.
Its value lies in its capacity to trigger myriad, complex responses in the human physiology.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com