Exact(5)
Yet these AChE isoforms have identical catalytic activity [63], differing only in their alternatively spliced C-termini [64].
To explore the evolution of ASEs, we had further explored connection between NAS mouse genes and their alternatively spliced human orthologs.
These arrays were designed to identify differentially expressed genes, but not their alternatively spliced transcript forms.
While transcript level data has been used previously to define gene-level orthologue groups, this appears to be the first work to examine and subdivide orthologue gene groups based on their alternatively spliced transcripts which often have differing functions.
The FGF family of ligands consists of 18 structurally related polypeptides that signal in paracrine or endocrine fashion through four FGFRs (FGFR1-FGFR4) and their alternatively spliced isoforms to regulate a myriad of biological processes in human development, metabolism, and tissue homeostasis.
Similar(55)
All we can do is call them from the back porch, listen for their mkgnao, or, alternatively, their mrkgnao, and offer our services gratis, just for the hell of it, and the mystery, and the fun.
Users can copy the scoria directory directly into their projects; alternatively, they can install Scoria via popular package managers (i.e., pip and conda).
Paradoxically, both the full length HMGCS1 and PCSK9 transcripts had significantly reduced transcript half-lives after sterol depletion while there was no change in mRNA stability of their respective alternatively spliced variants.
Leaching of chrysotile fibers decreased their reactivity; alternatively, leaching of crocidolite increased the effects on PMC.
For the tandem duplicated pair OsATG1a and OsATG1b, their different alternatively spliced mRNA forms showed different responses to various treatments (Figs 4– 6).
The receptors and their respective alternatively spliced isoforms are expressed in a cell- and tissue-specific manner, important for initiating specific responses to the ubiquitously expressed FGF family of growth factors.
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