Overall, L-GRAAL and HUBALIGN outperform all other aligners in terms of the topological quality of their alignments on the real networks from BioGRID (we also observe similar results when aligning binary PPIs only, see Supplementary Fig. S4).
Aligning the reads to the contigs simplifies their alignments to the reference by guiding them with the much longer contigs as backbone (see below).
We excluded 90 pairs after alignment because their alignments contained more than 24 gapped positions, leaving 1,813 aligned pairs of orthologs.
Armed with this information and following a knowledge-based approach, we used MODELLER v9.5 [64] to align the sequences and construct several models by changing their alignments with the kinase domain of hIKK-2.
They maintained their alignments with great precision.
Until they find their groove, the Giants will continue to experiment with their alignments along the defensive line.
(Ackroyd, another London obsessive, had read Sinclair's long poem, Lud Heat, a mystical account of Hawksmoor's churches and the significance of their alignments).
Their alignments, the way that they come out and distribute their receivers, that's something we have to pay attention to".
"He is complete, special, and the Rams do a great job with deception in their alignments of him to distort your defense," said Don Blackmon, the Falcons' defensive coordinator.
Interestingly, it is precisely Muslim oil-producing states — Libya, Saudi Arabia, Iran, (mostly Muslim) Kazakhstan, Malaysia — that seem the best at spreading their alignments across some combination of the Big Three simultaneously: getting what they want while fending off encroachment from others.
But the error turns out to correspond closely with the observed errors in the pyramids' positions: the further their estimated dates of construction are from this window of accuracy, the larger the errors in their alignments.
