The most weighty challenge posed for Duhem's view of science is, I think, this: if metaphysical assumptions can make a difference to science, who is to say that science will not be more successful if it is less neutral?
Mr. Zaslav, whose favorite phrase at meetings is "keep it going," now faces arguably bigger, more weighty challenges with three new channels, one for children with Hasbro, one in 3-D with Sony and Imax, and one with Oprah Winfrey.
"It's a very weighty challenge," Kevin M. Rampe, the president of the development corporation, acknowledged yesterday.
It is a weighty challenge - possibly the toughest in media sales - but the sort of gauntlet Howell will not be able to resist picking up when he bounds into ITV's Gray's Inn Road HQ for the first time.
Against that backdrop, the summit meeting is at best a weighty challenge and at worst a risky venture.
The title role, which she will sing, is another vocally weighty challenge.
Let's be clear, with global poverty soaring and the biosphere deteriorating, there are far weightier challenges for designers to wrestle with.
The weighty discussion mostly centres on the challenges of affection and longing.
The boldness and strength of the weighty new classical figures constituted a challenge for Ghiberti, but he met it with success in his next sculptures, and maintained his preeminent position as a leading artist in Florence.
