Exact(2)
We decided against a reassembly from the raw sequencing data that went into the 5 independent assemblies due to the varying error profiles of the raw data from different library preparation and sequencing chemistry.
Applying the same test on the global error rates showed a significant difference (P = 8.3 e-6, 95% confidence interval = [−0.16, −0.07]), most likely due to the varying error rates between the different error types (allele drop-out, allele drop-in) which can only occur when the reference genotype is either heterozygous or homozygous, respectively.
Similar(58)
These two schemes have advantages of their own: the reinforcement learning scheme offers more control on the stability of the sample path with varying error performance, and the modified RDS scheme based on short crawls is simple and has superior performance compared to the classical RDS.
Figure 4 shows the chimerism analysis varying error rate.
Table 2 reports the recall while varying error rates, number of clusters and k.
Figure 4 shows the percentage of NFI for mappers run in the 'all' mode with varying error rates.
Using the simulated data described in Section 3.2, we ran FastHap on variant matrices of varying error rates and compared the reconstructed haplotypes with the true haplotypes.
For stabilization, the problem is converted to an equivalent tracking problem, using a time varying error feedback, before the tracking control is applied.
The frequency of outpatient diagnostic errors is challenging to determine due to varying error definitions and the need to review data across multiple providers and care settings over time.
We simulated sequencing of these to 4X coverage each (12X for the most populous haplotype, 4X each for the remaining three) keeping the read length at 400 bp and varying error rate.
To indicate alignment accuracy evaluation for short-read datasets with varying error rate existing, the results are shown in Figure 5(a) for sensitivity and Figure 5(b) for precision comparison.
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