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The updated analyses show that changes to the Tokamak cooling water system design have enhanced confinement and reduced potential radiological releases as well as removing decay heat with very high reliability.
As reported by the updated analyses of BIG 1-98, this is translating into an OS benefit with longer follow-up [ 16, 49, 51].
In the updated analyses in November 2011, none of the 68 patients in arm A achieved CR, whereas of the 71 patients in arm B, 1 attained CR (%CR, 1.4%).
In the updated analyses, median OS and 3-year OS were 13.1 months and 25.9%, respectively, for arm A and 14.4 months and 25.7%, respectively, for arm B. Daily RT plus LDPF chemotherapy did not qualify for further evaluation as a new treatment option for patients with locally advanced unresectable esophageal cancer.
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Notably, these updated analyses show no substantial risk of cumulative toxicities or new safety signals despite a 60% increase in cumulative treatment exposure in the EVE+EXE arm.
First, about 10 years after the initiation of the service, updated analyses of the original data set by independent groups in Europe and the US found that the initial estimate of benefit in the reduction of breast cancer mortality was grossly exaggerated.
The authors report here updated analyses from the study, which are consistent with previously published results indicating that CRT-P or CRT-D has favorable effects on heart failure morbidity and mortality in a patient population "precision" selected by the surrogate marker of increased QRS interval duration.
Selective crossover disturbs the randomized comparison in updated analyses performed subsequent to first results and therefore particularly impacts the OS results, which require longer follow-up.
Our objective was to provide an updated analyses of the lung cancer cases from a multi-site international cohort study, including descriptive statistics of the demographics (age, sex, and race/ethnicity) of cases, as well the of histology.
Indeed, although a study based on data from a large dialysis organization did not identify an association between A1c level and survival during a 12-month follow-up period (6), updated analyses of the same study population were consistent with our findings, with increased mortality rates observed at extremes of A1c levels (5).
Our updated analyses are based on the vCJD deaths occurring to the end of December 2002.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com