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To understand how a ligand, typically a substrate or a regulator, binds to its macromolecular counterpart is a key issue in the understanding of function itself, and it is the basis of structurally driven drug design.
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Rodrigues, M. L., Nakayasu, E. S., Almeida, I. C. & Nimrichter, L. The impact of proteomics on the understanding of functions and biogenesis of fungal extracellular vesicles.
Still, there has been considerable progress into the understanding of functioning.
Structural biology has played a central role in the understanding of serpin function and biology.
Studying the structure, function, and redox properties of this protein is crucial to the understanding of the function of the entire heliobacterial cytochrome bc complex.
A plethora of conflicting observations about the physiological role of CLU has complicated the understanding of its function in tumourigenesis.
This development revolutionized the understanding of nervous function.
These techniques drive the understanding of macromolecular function at the atomic-level.
The understanding of cell function often requires that complex intracellular pathways are considered in quantitative terms.
Drosophila has only one PARP1 gene, making the understanding of its function relatively easier than in human cells with more than 17 PARPs.
The theoretical model of thermotaxis developed here furthers the understanding of the function of a cell as a thermal and chemical sensor.
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