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As embryos develop, the gamete-inherited chromatin states are rewritten in somatic cells but maintained through the five cell divisions that generate the two primordial germ cells (PGCs) present in newly hatched larvae12 (Fig. 1d).
The nature and extent of the conjunction result from the initial reciprocal distance and position of the two primordial discs on the yolk sac or amniotic cavity.
The clearest case is present in Plateosaurus, which has a unique sacral configuration among basal sauropodomorphs [56], [57], composed by the two primordial sacrals plus a caudosacral (S1+S2+CS; Figure 16).
Comparisons between the two specimens suggest that the complete sacral configuration of Melanosaurus readi includes two dorsosacrals, followed by the two primordial sacrals, and a single caudosacral (A. Yates, pers. com).
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The Daoist treatise Huainanzi (book of "Master Huainan") describes how the one "Primordial Breath" (yuanqi) split into the light ethereal yang breath, which formed heaven; and the heavier, cruder yin breath, which formed earth.
This leads to decline in the three primordial as well as proximate chronic disease risk factors.
Probe sets were used for a multiclass Significance Analysis of Microarray to determine if their mean expression was different across the three mammary epithelial cell (MEC) subpopulations described in [ 5] and the three primordial populations.
The reprogrammed cells were termed induced pluripotent stem cells (iPSCs), and are similar to embryonic stem cells (ESCs) in their morphology, proliferation, surface antigens, gene expression and capacity to differentiate into the cell types of the three primordial germ layers.
Expression data were normalised and summarised by robust multi-array analysis (RMA) using the affy package in R. Probe sets were used for a multiclass Significance Analysis of Microarray (SAM) to determine if their mean expression was different across the three primordial populations.
In 1937 the South African Alexander Du Toit modified Wegener's hypothesis by suggesting the existence of two primordial continents: Laurasia in the north and Gondwanaland in the south.
There is a possibility that the recent LIGO detection of gravitational waves originated from the merger of two primordial black holes, making up the dark matter.
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