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Statistical difference between bone formation of the two groups were calculated using Mann-Whitney U test.
The changes in bone width and height between the two groups were calculated, and Mann-Whitney U test (SPSS Inc., Chicago, IL, USA) was used to evaluate statistical significance.
For comparisons of oocyte numbers, differences between the two groups were calculated with Student's t-test, and a difference was considered significant if P<0.05.
Subsequently, differences between the two groups were calculated to determine Christmas specific brain activation.
Differences between the two groups were calculated by log-rank test.
Also Fold Changes (FC) between the two groups were calculated for each gene.
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The statistical significance of the difference in number of responders after three vaccinations in the two groups was calculated with a Fisher's exact test.
(2) The difference of RM between the two groups was calculated.
For each resampling, the mean difference between the two groups was calculated.
Identification of genes differentially expressed between the two groups was calculated using limma as described above.
The PFS of patients in each of the two groups was calculated using the Kaplan-Meier method.
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