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The interpenetration does not occur to partially encountered segments of the two globules, even though the chain segments are in the molten state.
Molecular dynamics was performed in a model system of two chain globules so that a process of the two globules merging was just simulated.
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In the first stage, the touched two globules change their shapes rapidly from a sphere to a half-ball respectively.
The equivalent weight of each of the two terminal globules is approximately 30,000; the molecular weight of myosin is close to 500,000.
Purified FilGAP molecules appeared to be flexible dumbbells with two globules (∼14.2+/−2.05 nm diameters; n = 50) orienting at various angles.
Electron micrographs of the distal end of the long arm of the cross-shaped laminin molecules reveal LG1-3 as three globules in a triangular arrangement and in close contact with the rod-shaped coiled coil.
The positive ThT emission which is characteristic of aggregation further suggests that ribosylated α-Syn molecules exist in molten globules.
The two arrays of eyespot globules, the associated thylakoids, and the bordering chloroplast envelope were all slightly concave relative to the plasma membrane.
Upon cytochrome c binding to Apaf-1, the WD-7 domain rotates to accommodate the cytochrome c globule between the two WD domains [ 24– 26].
We recently identified a structure that topologically corresponds to the lipid ester globule between the two membrane leaflets of the ER in cultured hepatocytes (Fig. 6) (Ohsaki et al. 2008).
The same reason explains the reason behind (conspicuous) absence of all-β classes from molten globule state of a protein [67], [68].
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