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While the electrophoretic polymorphism is not due to the duplication, the observation of a heterozygous genotype for an inbred strain may well have been due to a polymorphism between the two duplicate copies (modern AKR/J mice have the duplication; Figure 3).
The duplication-degeneration-complementation (DDC) model predicts a third alternative, in which the two duplicate genes become permanently preserved as a consequence of complementary, degenerative mutations that result in partitioning of ancestral subfunctions, so that the sum of the functions of two paralogs equals the functions of the original gene prior to the duplication [ 2, 3].
A tenfold dilution series of the pooled cDNA from the two duplicate RNA samples from LSBJ or RSC02 was used for the qPCR experiments.
The two duplicate characters are Ippo and Mamoru Takamura.
Therefore, the two duplicate copies of foxi3 genes may have been preserved during vertebrate evolution by a sub-functionalization mechanism.
All the significant target sets of miRNAs and GO terms were tested/cross-tested in the two duplicate developmental cerebellum mRNA expression series.
Similar(36)
After gene duplication the two duplicates have the same interaction partners.
Tandem duplications are special types of duplications, where the two duplicates are adjacent.
We generated a phylogenetic tree of all TFIIAγ or TFIIAγ-like sequences to explore the duplication history of the two duplicates.
Without gene conversion, the two duplicates are assumed to evolve independently after the duplication event, such that πind should be expected to be significantly higher than πdupl.
The two duplicated gene families that my thesis considers are phytochromes and gibberellin3‑oxidases.
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