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The trial employed a non-inferiority design.
The trial employed a 'before and after' and 'with and without' design.
The trial employed frequent sedation assessment, daily sedation stops, and a double-dummy design to reduce the risk of bias.
The trial employed a single lifetime HPV test in a setting where essentially no other HPV testing was performed.
Because non-opioid analgesia is not always taken at sufficient doses to achieve pain control [ 24] the trial employed a run-in period during which analgesia was optimised.
These include whether the trial employed a patient-centered or surrogate measure as the primary outcome, evaluation of the strength of association between the intervention and primary outcome (for example, relative risk or odds ratio), assessment of the precision around the effect estimate (for example, confidence limits), and determination of the baseline or control group observed event rate.
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The trial employs central, stratified randomisation which secures against selection bias.
The trial employs a wait-list control design: participants in the standard-care arm switch to self-testing arm in the second year, and gain access to self-test kits.
However, the trial, employing a high-risk sample that reported many syndemic psychosocial conditions, including childhood abuse victimization, intimate partner violence, and alcohol dependency [ 73], went beyond previous trials in drawing attention to the mediating mechanism in a theory-based intervention.
The NZ study outlined the importance of involving experienced Maori researchers at each time point of the trial, employing experienced Maori researchers, who used culturally specific processes for participation and retention of Maori participants and ongoing contact with Maori researchers and participants [ 24].
The trials employed the obsolete ironclad, modified with armour protection identical to that used by the s then under construction.
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CEO of Professional Science Editing for Scientists @ prosciediting.com