In terms of surgical planning, the decision to resect or preserve the neurovascular bundles can have tremendous consequences in the long-term morbidity of the procedure, to the extent that some surgeons will preferentially consider nerve-sparing procedures combined with adjuvant radiation therapy in the presence of positive surgical margins.
The development of multi-drug resistance in corynebacteria is probably enhanced by the selective pressure occurring in the hospital setting and has tremendous consequences for the successful treatment of human infections, especially in elderly individuals and in immunocompromised patients [ 12, 13].
"How you respond to these issues will have a vital impact on the next phase of the Internet economy, with tremendous consequences for American jobs, standard of living and competitiveness," the executives wrote.
In the realm of education, however, there's a particularly corrosive shift that's taking place, one that has tremendous consequences for the development of America's best minds: the growing gap between super-wealthy colleges and universities — and the rest of the academic world.
Child abuse and neglect (CAN) is a serious problem, and an improper diagnosis carries tremendous consequences for the patient, his or her family, and the doctor.
This illustrates how, in a P2P DHT, the relative link between a node's logical and physical locations can have tremendous consequences for the DHT's overall performance.
"It would be very surprising if Tibetans who set themselves on fire, especially nuns and monks trained in the field of causality, were not conscious of the fact that their actions can have tremendous consequences and can capture the discontent and frustration of their compatriots," said Christophe Besuchet, writing on the Web site of a vocal exile group, the Rangzen Alliance.
And that is a choice that will have tremendous consequences for the country".
It's that who runs Medicare, and how he or she runs it, will have tremendous consequences for the health-care system as a whole.
This is, as we think, a nice example of the tremendous practical consequences the introduction of a new class of anticancer drugs could and even should have.
