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Moreover, an additional tree derived from the MEME results, analyzing the Dof domain plus all the conserved motifs described in Table 3, presented the same group and subgroup organization as the tree displayed in Figure 2A (data not shown).
Age and two or more positive scores on the VMS domains were the strongest predictors of an adverse outcome.> -wrap-foot> > -wrap-foot> treetree displayed in Figure S2, Supplementary data available in Age and Ageing online, was composed by the performance of a CART analysis including age, type of admittance and all information extracted from the VMS screening.
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The incremental cost-effectiveness analyses were designed as a decision analysis where a reference population of 1,000 suspected malaria patients in each diagnostic option (RDT or current practice) in the two settings was exposed to the decision tree displayed in Figure 1.
We also studied the evolutionary relations of all human Hsp70 proteins (excluding HSPA12A and HSPA12B) with prokaryotic DnaK(Hsp70) proteins, resulting in the evolutionary tree displayed in Figure 4 that shows the close relation of HSPA9B (mitochondrial) with alpha-proteobacterial sequences.
The phylogenetic tree displayed in Figure 1 was created by ClustalW2, with the default multiple-sequence-alignment matrix (Gonnet 250) and is displayed as an unrooted maximum-likelihood tree from TreeView, version 1.6.6 [ 71].
The SNP at position 3 in this block separates 011 from the other alleles in this tree, but this SNP also groups 011 with 001 and 111, which are recombinant alleles that do not fit in the parsimony tree displayed in Figure 3.
However, the seasonal variation of the percentage oil yield from these 17 trees displayed in Figure 4, shows two trends: trees #7 and #16 (L. liversidgei chemotype I) have a greater percentage oil yield in spring and other Leptospermum trees have a greater percentage oil yield in summer.
The TPS and TPP trees displayed in Figures 3 and 4 show similar overall topologies, confirming that there is a high evolutionary correlation between TPP and TPS domains, which was suggested by the fusion of both domains in most of eukaryotic proteins and their clustering in the prokaryotic genomes (see Additional file 8).
Therefore, it is unlikely that nucleotide composition bias can explain the phylogenetically "misleading" observed among clades I to VII in ML trees displayed in Figures 1, 2, 3 and 4.
A Bayesian analysis with the LG model was used and the resulting tree is displayed in figure 3. The full tree without collapsed branches is given in supplementary figure S2, Supplementary Material online.
Results of the relative predictive accuracy of the best bootstrapped tree compared to the CART tree are displayed in Figure 4.
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