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Three subjects were unable to complete the treatment due to illness unrelated to their sleep problems; 19 subjects completed the treatment (completion rate being 86%).
FDG-PET positivity at the treatment completion is an adverse prognostic factor for disease-free survival [9].
The additional cost of DOT for patients and their families is substantial, and may be contributing, in Rio de Janeiro, to the treatment completion rates below the targeted 85% recommended by WHO.
Because of the modest increase in the treatment completion rate with DOT, the ICER was high: US$ 6,616 for the health system and US$ 1,780 for the patient.
The treatment completion rates were 72.3% and 71.8%, respectively, without significant difference (Table 2).
The main difference was that the treatment completion rates were lower.
Similar(41)
If the patient experienced an adverse event (AE), the treatment-completion date and time for that AE was recorded as the IRLOS end.
In the other study by Al-Noseery 27 including patients from the same center, the percentage treatment completion rate was 77%.
The protocol treatment completion rate in the S-1 and UFT/LV group was 76.5% and 73.4%, respectively, with no significant difference (P = 0.171).
One had completed 6 months of treatment; for the other, treatment completion was not recorded.
The feasibility of S-1 treatment as an adjuvant chemotherapy for colorectal cancer was confirmed by ACTS-CC [ 4], although the protocol treatment completion rate remained 76.5%%.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com