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The conserved genes complement the TraSH data to arrive at a catalogue of 'minimal gene set' that Mycobacteria require for their survival and hence pathogenicity.
The strains grew identically during the batch phase (results not shown) but had a significantly reduced fitness during slow growth rate, independently confirming the TraSH data (Figure 4).
To clarify the situation, and also to independently validate the TraSH data, an individual gene knock-out of glpK was constructed in both M. bovis BCG and M. tuberculosis.
The TraSH data set provides microarray signal ratios that represent the relative abundances of each mutant in the TraSH library.
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"When we're evaluating child access laws, we're using total trash data," said Catherine Barber, a researcher at the Injury Control Research Center of the Harvard School of Public Health.
As has been reported previously there was a very poor correlation between the transcriptome of slowly growing BCG and the TraSH essentiality data [6], [7].
I'd love nothing more than to dump them in the trash and let my data storage and the tech problems associated with it become Google's headache.
Analysis of metagenomic data from the trash reads allowed for the collection of 1189 reads corresponding to the genome of the Akkermansia muciniphila type strain (ATCC BAA-835), which has a G + C content of 55.8%.
The data is piling up like the trash in our landfills.
We utilized the transposon site hybridization (TraSH) mutagenesis data set utilized to validate the original GSMN-TB model [ 43, 108].
Upbeat wants to use data science to create PR pitches that don't automatically end up in the Trash folder.
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