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Concurrently, the toxic threshold and identification of potentially useful toxicity biomarkers of SWCNTs-induced hepatotoxicity were also studied by conventional clinical chemistry and histopathological examinations.
Eventually, the toxic threshold is reached and injury will develop.
The toxic threshold used in this paper was the BMD5.
This study was designed to estimate the toxic threshold of male and female fish to microcystins based on different biomarkers.
The optimal catheter position is located by a novel optimization technique, which simultaneously maximizes drug concentration in the desired brain region, while ensuring that the final drug concentration does not fall below a therapeutically effective level or rise above the toxic threshold in non-treatment areas.
Risk assessment showed that Hazard quotients for Heptachlor epoxide, Dieldrin, Endrin and Aldrin were above the toxic threshold of 1.
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Our results suggest the embryonic growth and hatchability tests are useful endpoints in chronic sediment toxicity tests for determining the toxic thresholds of ENPs in sediment environment.
The wastewater is expected to have a higher threshold of terephathalate toxicants and only organisms with well-adapted USP genes will proliferate at this toxic threshold.
15 We did not measure the plasma ropivacaine concentrations in the present study, for it has been reported that the total plasma concentration of ropivacaine remains far below the known toxic threshold when larger amounts of ropivacaine are used.
Dopamine turnover also showed significant increases after CPF exposure on GD17-20, but only when the dose was raised above the threshold for overt toxicity; however, hippocampal dopamine content was profoundly subnormal after exposures below or above the acute, toxic threshold, suggesting outright neurotoxicity.
Dopamine turnover also showed significant increases after CPF exposure on GD17 20, but only when the dose was raised above the threshold for overt toxicity; however, hippocampal dopamine content was profoundly subnormal after exposures below or above the acute, toxic threshold, suggesting outright neurotoxicity.
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