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These interconnections are typically formed by three patterning steps, each of which have an impact on the series resistance and consequently on the total module performance.
The total module overlap (TMO) was computed as the sum of all of the module overlap scores for both the positive and negative gene lists; i.e. TMO Q+,Q−) = 1/2 * (SO(Q+) + SO(Q−) + DO(Q+) + DO(Q−)).
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Total module disparity was defined as the sum of the partial Procrustes distances for all specimens for only the landmarks within each module.
By deleting the missing values from the Treatment II Scale from the calculations, missing value percentages for the total cardiac module decrease from 15.0%to5.4%4% for child self-report, and from 14.6% to 4.8% for parent proxy-report.
After comparing the median-LNS with WGCNA connectivity-based statistics, we found that median-LNS correlated best with bicor.kMEall, which is the correlation of the total network module eigengenes connectivity.
Indeed, in Stensola et al. (2012), 4 5 modules were discovered in recordings spanning up to 50% of the dorsoventral extent of MEC; extrapolation gives a total module number consistent with our estimate.
Total module cost was found to be most sensitive to the plastic substrate prices, while the production rate did not have a significant impact on module cost for rates above~50 m2/min.
This metric is the ratio of the total in-module degrees of the vertices to the total number of their connections and depicts how well connected are the members of the module.
We assume that any given pre-synaptic neuron n is only connected to a subset m of the available modules; thus the total number of modules in the volume may, but need not, exceed m.
Gene to module assignments were first randomized, while preserving the total number of modules, the number of genes per module, and the number of modules to which each gene belongs as in Suthram et al. [ 16].
Through implementation of ResMod to correct for resolution limits by optimising each of the five communities further without considering the inter-module links, the two smaller groups within each module become apparent and the total number of modules is correctly identified as ten.
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