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The Toronto study concluded that it was the conversation itself -- and not simply use of the phone -- that distracted drivers, a point echoed by Ms. Mount.
Others, including Dr. Allan S. Detsky, an author of the Toronto study, take a less stringent view, arguing that conflicts should be made public and that doctors should discuss them openly before writing guidelines.
"It's understandable that there's confusion because D.C.I.S. and breast cancer are both detected the same way and they're treated very similarly," said Dr. Eileen Rakovitch, a radiologist and lead author of the Toronto study.
Only 7percentt of the doctors in the Toronto study said they believed that their relationships with industry influenced their recommendations, although 19percentt said financial ties influenced the recommendations of their colleagues.
All studies except the TORONTO study included incident endometrial cancer cases exclusively.
No heterogeneity of effects was observed between the TORONTO study and studies including incident cases only (p = 0.78).
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Most studies recruited population controls only, whereas two studies recruited also hospital controls (319 and 353 in the MLCS and TORONTO study, respectively).
Information on ovariectomy (defined as bilateral ovary removal) and hysterectomy was collected in four (EAGLE, ESTHER, MLCS and TORONTO) and three (ESTHER, MLCS and TORONTO) studies, respectively.
Details of the Toronto site recruitment and study design have been described previously [ 27].
Thus, 120 homes analyzed for the suite of hopane monomers by December 2010 were included in this study; 2 The Toronto Child Health Evaluation Questionnaire (TCHEQ) with 1,500 subjects from a nested case control study were randomly selected from a larger survey of 5,619 students who completed a screening survey for respiratory disease [ 24].
A study of the Toronto newborn sample used population norms to identify impairment on the revised Yale Developmental Inventory in toddlers.
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