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Further analysis of the top two processes (Cellular Processes and Immune Response) is shown in Figure 3.
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The top five processes include anatomical structure development (13.8%), signal transduction (9.7%), immune system process (7.5%), response to stress (6.3%), and cell differentiation (5.8%).
The top ten processes for each of the heterodimers formed by RXRα and other nuclear receptors were investigated in this study (Table 1).
Table 2 lists the top ten processes based on the number of assigned protein families and grouped them according to the trophic ecology of the species (a complete list of the mappings to the Panther protein classification system is available as Additional file 1).
Gene overlap between pathways was relatively low, with 367 (73%) of the 500 genes in the top four processes (RNA splicing, DNA repair, protein modification by small protein conjugation and viral reproduction) unique to only one of these pathways (Additional file 1: Figure S9).
The top two biological process categories identified in that analysis were "response to stimulus" and "multi-organism process".
The top three biological processes were metabolic processes (20%), cellular processes (18%) and response to stimuli (12%).
These top four processes were relatively distinct from the individually most strongly sex-associated CpG sites, with only 10 genes from these processes represented in the CpG sites which passed Bonferroni correction.
As metabolic processes are the most active process in fruit development, it is understandable that cellular processes and metabolic processes were the top two GO terms within biological processes.
To confirm the results and further explore the managerial implications, a second session of focus group meeting was conducted and practices of the top three key processes in the semiconductor manufacturing industry were used to illustrate what actions can be performed to improve these processes and hence benefit the entire SC network.
Table 1 gives the top four biological processes that are most significantly enriched in the active clusters in the final iteration, in terms of the score averaged from the 100 validation experiments.
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CEO of Professional Science Editing for Scientists @ prosciediting.com