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In one study, cardiac stem cells were isolated via endomyocardial biopsies of explanted hearts or at the time of left ventricular assist device implantation.
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For heterotaxy cases, this requires assessing mRNA or protein levels at gastrulation (the time of left-right axis formation); a task not possible for human cases of heterotaxy.
At the time of left-right axis formation, the mutant transcript is not subjected to NMD, predicting the production of a mutant protein during embryogenesis.
These data indicate that the Zic3 transcript is a poor substrate for NMD at the time of left-right axis formation and raise the possibility that the Ka mutation does not represent a null allele.
"The time of the Left has finally come," said a group of young women standing next to me.
This is - perhaps naturally at the time of a centre-left government - most strongly believed by commentators on the right.
Tricuspid repair should be considered at the time of surgery for left-valve disease in cases of more than trivial TR and dilated annulus.
TR is most often diagnosed at the time of echocardiographic evaluation of left-side heart disease or evaluation of right heart failure.
Geomagnetic observations only provide the time series of (left ({{g_{l}^{m}}}, {{h_{l}^{m}}}right)).
Tau is the time constant of left ventricular relaxation during isovolumetric diastole.
Solid line: GCaMP5; dashed line: RFP, the two black arrow heads indicate the time points of left and middle panel in (B ).
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CEO of Professional Science Editing for Scientists @ prosciediting.com