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FC carried out the collection of data regarding the testing population, and contributed to the drafing and critical revision of the manuscript.
When the optimal number of PC was determined based on realized accuracy in the testing population, PCR showed a higher potential in terms of achievable accuracy that was not capitalized when PC selection was based on cross-validation.
In each scenario, we assume that the target population is the same as the testing population and examine how well different models generalize for different target populations and what are the characteristics of the trait that make such generalization possible.
Here we consider two scenarios, within-cohort prediction, in which case the training, validation and testing sets come from the same population cohort, and across-cohort prediction, in which case the training and testing sets come from different populations and the validation set comprises samples either from the training or from the testing population.
The ability of the score to predict the outcome glycemia ≥ 140 mg/dl control at discharge and the best cut off value of the score were assessed by measuring the area under the receiving operating characteristic (ROC) curve in the testing population [ 30].
Given the complex breeding history of an AIL populations, however, the assumption of independence is formally incorrect, and this can become a serious problem depending on the details of the construction of the testing population (N) from the breeding population (Nb), following Darvasi and Soller's nomenclature.
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EC50 lowest identified effect concentration where 50% of the tested population have been found to be affected.
We ran additional analyses to assess the effect of age in the tested population.
The haplotypes of HvNAM1 explained 20.6% GPC variance in the tested population.
A close inspection of the data indicates two subgroups within the tested population.
The prevalence of progressive CKD was expressed as a percentage of the tested population.
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