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The test of interaction between cisplatin and erlotinib was conducted on the interaction term using a one-sided Wald statistic to determine whether β3>0, indicating synergy, defined as a more than additive effect.
The test of interaction was marginally significant (p = 0.05, Table 3).
A P value < 0.05 for the test of interaction was considered statistically significant.
The test of interaction between non-pharmacological and pharmacological trials was not significant (P=0.84).
If the test of interaction is not significant, the tests of the main effects are not confounded.
The choice of effect measure for the test of interaction should therefore be specified before analysis of the data.
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The tests of interaction were not significant.
The tests of interaction between objective physical function and mortality by cancer type are provided in the online Supplementary Results.
One of the underlying assumptions of the tests of interaction with E as the response, EGT, EGD, and EGG, is that E is normally distributed.
This includes that the tests of interaction between gender and gendered life on mental ill-health could generally not be statistically verified.
However, some caution should be used in the interpretation of this result given the lack of statistical significance in the testing of interaction between the cohort group and sex.
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CEO of Professional Science Editing for Scientists @ prosciediting.com