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This stems not only from an incomplete knowledge of the targets that contribute to unconsciousness (1, 4), but also from the targets underlying isoflurane's neurotoxic and "preconditioning" effects (6).
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Asperparalines produced by Aspergillus japonicus JV-23 induce paralysis in silkworm (Bombyx mori) larvae, but the target underlying insect toxicity remains unknown.
Identifying the candidate targets underlying the genomic aberrations was important for understanding the mechanism of carcinogenesis.
However, the molecular targets underlying the cellular effects induced by inhibition of the BRAF pathway in thyroid cells remain to be determined.
In the attempt to identify the molecular targets underlying QRs internalization at acidic pH, we tested the involvement of annexin XII (ANX), a Hydra protein belonging to the annexins superfamily [29], [30], able to insert into lipidic membranes and to form ion channels at acidic, but not neutral pH [31].
The data will provide the research community important insight into the relevant targets underlying asbestos-associated lung cancer.
This has allowed the discovery of new targets for established drugs, suggested the bases for their side effects, and predicted the molecular targets underlying phenotypic screens.
However, given the diverse variety of cellular binding sites for cholesterols [ 334], unraveling the specific molecular targets underlying the antiviral effects of 25OHC will be challenging.
The estimation of articulatory targets underlying the movements due to these factors allows us to capture the trend of the variability, which can be then summarized into a single contextually invariant target by the analysis of parameter distribution [21, 22].
Although extensive genetic studies have been performed demonstrating an essential role for Twist1 in limb patterning and morphogenesis, the direct transcriptional targets underlying these functions are only recently being elucidated [ 12].
Fig. 4 The promiscuity of ligand clusters and targets underlying the LCBN.
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com