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However, little is known about their repertoire of differentiation capacities, how closely they resemble the target primary tissues, and the potential safety issues associated with their use.
For experiments that involved dual labelling of virus and cellular compartments, the specificity of the secondary antibodies for the target primary antibody was confirmed by showing a lack of cross-reactivity with non-target primary antibodies.
Because many of the target (primary) phenotypes of research studies are complex conditions or disorders, data are commonly collected on multiple risk factors and comorbid conditions.
For the detection and quantification of unspecific binding due to Fc receptor binding or other protein-protein interactions mouse IgG1/IgG2a isotype controls (Miltenyi Biotech GmbH) were used at identical concentrations and staining conditions as the target primary antibodies.
Moreover, the simulator should enable us to answer the following questions: (1) Is the ability to keep haemoglobin within the target (primary end point) and haemoglobin stability (secondary end point) influenced by the erythropoietin half-life and administration interval and/or by the use of the simulator (learning effect)?
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The first part consisted of target, primary collimator, flattening filter, monitor chamber, and mirror.
In these animals, the lower respiratory epithelium was the target for primary replication of virus.
The target included the primary tumor and the metastases of the right pelvic bones.
In addition to the tumor, the primary target cells are endothelial cells in blood vessels.
APAP induced LTB4 production in the liver, the primary target organ in APAP toxicity.
The target tissue as the primary driver of the axial elongation has remained elusive so far.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com